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KMID : 0384620080190040247
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Korean Journal of Medical Physics
2008 Volume.19 No. 4 p.247 ~ p.255
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Coded Aperture Gamma Camera for Thyroid Imaging: Monte Carlo Simulation
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Beak Cheol-Ha
Chung Yong-Hyun
Lee Seung-Jae
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Abstract
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A coded aperture camera has been developed to improve the signal-to-noise ratio (SNR) while keeping the spatial resolution of a pinhole gamma camera. The purpose of this study was to optimize a coded aperture camera and to evaluate its possibility for thyroid imaging by Monte Carlo simulation. A clinical gamma camera, a pinhole collimator with 1.0 mm hole diameter, and a 79x79 modified uniformly redundant array (MURA) mask were designed using GATE (Geant4 Application for Tomographic Emission). The penetration ratio, spatial resolution, integral uniformity and signal-to-noise ratio (SNR) were simulated and evaluated as a function of the mask thickness. The spatial resolution of the coded aperture camera was consistent with the various mask thickness, SNR showed a maximum value at 1.2 mm mask thickness and integral uniformity was improved by increasing mask thickness. Compare to the pinhole gamma camera, the coded aperture camera showed improved SNR by a factor of 30 while keeping almost the same spatial resolution. In this simulation study, the results indicated that high spatial resolution and ultra-high SNR of the thyroid imaging are feasible using a coded aperture camera.
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KEYWORD
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Coded-aperture, Pinhole, Gamma camera, CATE simulation
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